In vitro α-amylase and α-glucosidase inhibitory potential of Pleurotus ostreatus cv. Florida extract

Ganeshpushkar, Aditya ; Agrawal, Deepak ; Chourasia, Ayushi ; Shrivastava, Abhishek ; Dubey, Nazneen

Abstract

Pleurotus ostreatus cv. Florida is one of the widely used edible mushroom. The polysaccharides from this mushrooms have been studied for antidiabetic potential; however, no efforts have been made to explore the potential of this mushroom to influence carbohydrate metabolizing enzymes viz. α-amylase and α-glucosidase. The present work was undertaken to investigate the inhibitory potential of Pleurotus ostreatus cv. Florida on enzymes α-amylase and α-glucosidase. Several concentrations of extracts were used to study inhibition of enzymatic activity of α-amylase and α-glucosidase. A dose dependent inhibitory effect on enzymes was observed. The current study, for the first time, uncovered α-amylase and α-glucosidase inhibitory potential of Pleurotus ostreatus cv. Florida. The study could be helpful to isolate and characterize compounds responsible for it.

Keyword(s)

α-Amylase; α-glucosidase; Pleurotus ostreatus cv. Florida; Oyster mushroom

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