The pharmacological potential of catechin

Ganeshpurkar, Aditya ; Saluja, Ajay

Abstract

The contemporary scientific community has presently recognized flavonoids to be a unique class of therapeutic molecules due to their diverse therapeutic properties. Of these, catechin, also, has been explored for a number of pharmacological effects. The present review aims to document the therapeutic potential of catechin. Tea leave, catechu, and much more possess catechin as one of the active constituents. Today, catechin has been observed for its nutraceutical effect. The objective of this review is to examine the evidence of the effectiveness and pharmacological effects of catechin. Preclinical, as well as randomized controlled clinical trials pertaining to studies of catechin,are included in the study. Chemical properties of catechin and its structure-activity relationship about various biological activities have also been documented. The review revealed protective effects of catechin on functions and integrity of liver, kidney, heart , and age-related memory impairment. Catechin demonstrated the antimicrobial, anticancer, antihypertensive, anticoagulant , and antiulcer effect. The present review highlights the current information and the health-promoting effects of catechin. Along with this, the chemotherapeutic potential of the same has also been discussed.

Keyword(s)

Anticancer; Antidiabetic; Antimicrobial; Organ protection; Polyphenol

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