A new cinnamic ester derivative from Glochidion velutinum leaves and evaluation of its antioxidant and antibacterial activity

Abstract

The plant Glochidion Velutinum (GV) family Euphorbiaceae, a medicinal plant, is reported to possess various therapeutic applications such as antidiabetic, anticancer, antioxidant, antimicrobial, anti-inflammatory etc. However, the compounds responsible for therapeutic value have not yet been isolated. The present study reports the isolation of a compound from the leaves of GV. The compound is identified as a cinnamic acid derivative (p-pentadecayl ethyl cinnamate) through extensive spectral studies. Its antioxidant nature such as DPPH free radical scavenging assay, total antioxidant capacity, and antibacterial activity have been evaluated. The compound exhibited lower antioxidant properties compared to the standard. It has shown moderate antimicrobial activity against ten bacteria and significant antibacterial activity against Proteus Vulgaris compared to standard ciprofloxacin.