Silver nanoparticle modified Pt electrode as voltammetric and electrochemical impedance sensor for hydrogen peroxide in live biological cells

Das, Diganta Kumar


A non-enzymatic electrochemical sensor for hydrogen peroxide based on silver nanoparticle (AgNP) modified platinum electrode has been fabricated by multiple cyclic voltammetric scan of platinum electrode in AgNP solution in aqueous medium. The modified electrode (Pt/AgNP) can detect hydrogen peroxide in aqueous medium, bovine serum albumin  and live L6 rat myoblast cells with high sensitivity and selectivity by cyclic voltammetry and electrochemical impedance spectroscopy. The limit of detection of Pt/AgNP towards H2O2 is 5.4×10-7 M. The detection of H2O2 by Pt/AgNP is free of interference from Na+, K+, Ca2+, Mg2+, dopamine and ascorbic acid.


Electroanalytical chemistry, Sensors, Nanoparticles, Silver nanoparticles, Hydrogen peroxide, Cyclic voltammetry, Electrochemical impedance spectroscopy

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