Microwave assisted synthesis of hybrid heterocyclics


Srinivas, A

Abstract

Treatment of 2-(2-((3aR,4S,6S,6aS)-6-((1-(4-chlorophenyl)-1H-1,2,3-triazol-4-yl)methoxy)-2,2-dimethyltetrahydrofuro [3,4-d][1,3]dioxol-4-yl)-4-oxo-3-phenylthiazolidin-5-yl)acetic acid o-phenyl diamine in conventional and microwave irradiation gives 5-((1H-benzo[d]imidazol-2-yl)methyl)-2-((3aR,4S,6S,6aS)-6-((1-(4-chlorophenyl)-1H-1,2,3-triazol-4-yl)methoxy)-2,2-dimethyl tetrahydrofuro[3,4-d][1,3]dioxol-4-yl)-3-phenylthiazolidin-4-one. Characterization of new compounds has been done by means of IR, NMR, MS and elemental analysis.

 


Keyword(s)

Hybrid heterocyclics, click reaction, Knovenagel condensation, microwave assisted synthesis, antibacterial activity

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