Synthesis and characterization of γ-Fe2O3/polyaniline-curcumin composites

Li, Yongli ; Zhu, Chunxia ; Kan, Jinqing

Abstract

Superparamagnetic nanomaterials are showing great prospects in medical treatment with targeted medicine. A new conductive superparamagnetic nanocomposite, γ-Fe2O3/polyaniline-curcumin (γ-Fe2O3/PANI-curcumin), has been synthesized using the interaction between amino group in polyaniline and ketone group in curcumin. The γ-Fe2O3/PANI-curcumin composite has the superparamagnetism (30 emu·g-1) and electrochemical activity based on the results of magnetization curve and cyclic voltammetry (CV). Transmission electron microscope (TEM) shows that the particle size of γ-Fe2O3/PANI-curcumin is about 50 nm. Fourier transform infrared spectra (FTIR) and X-ray diffraction (XRD) have been used to characterize the γ-Fe2O3/PANI-curcumin composite and to confirm that curcumin is immobilized into γ-Fe2O3/PANI chains. The study provides an academic foundation for developing some new material for immobilizing drugs of anticancer.

Keyword(s)

Curcumin; Fe2O3/polyaniline-curcumin Maghemite; Nanocomposites; Polyaniline; Superparamagnetism

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