Synthesis of indole based novel symmetrical nitroolefinic dendritic core through n-arylation route

Sivakumar, M N ; Sathya, V ; Venkatesan, N ; Heera, T R

Abstract

Synthesis of indole based novel symmetrical nitroolefinic dendritic core has been succeeded using N-arylation route followed by Henry reaction. Synthesized symmetrical 1,3,5-triindolyl benzene has been successfully synthesis of by N-arylation of indole, symmetrical 1,3,5-tri(3-formyl indolyl)benzene and 1,3,5-tris(3-((E)-2-nitrovinyl)-1H-indol-1yl)benzene followed by Hendry reaction. These nitroolefinic cores have potential application in theoretical and medicinal chemistry and also used to prepare many new organic compounds of indole derivatives.


Keyword(s)

Dendritic core; Henry reaction; Indole; N-arylation; Nitroolefin

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