Silk biomaterial for skeletal tissue engineering

Abstract

Increased fracture rates and problems connected with missing bones as a result of accidents or various illnesses cause serious socio-health issues. Tissue engineering strives to provide a technique for promoting the healing or restoration of injured tissue as closely as feasible to the original tissue. The construction of scaffolds made from recombinant proteins is one of the most important alternatives proposed by this specialisation. Silk in bone tissue engineering has been extensively studied and the current study summarises the literature on such materials and their fabrication.