Antiproliferative potential of Sargassum binderi Sonder ex J. Agardh mediated biogenic silver/silver chloride nanoparticles on EAC, MCF-7 and HCT116 cells

Ahmed, M S ; Rahman, M M ; Hasan, I ; Kabir, S R ; Asaduzzaman, A K M

Abstract

Biosynthesis of Ag/AgCl-NPs from Sargassum binderi extract was confirmed by colour changes and a sharp peak at 416 nm detected by UV-visible spectrophotometer. It was characterized by Transmission Electron Microscopy (TEM), Energy Dispersive X-ray (EDX) spectrophotometer, X-ray powder Diffraction (XRD) and Fourier-Transform Infrared Spectroscopy (FTIR). Mild toxicity of the synthesized Ag/AgCl-NPs was determined by the brine shrimp nauplii cytotoxicity assay. IC50 values of 19.73, 25.56, and 14.00


Keyword(s)

Ag/AgCl-NPs, Apoptosis, Cancer cell inhibition, Gene expression, Sargassum binderi


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