Mosquito repellent activity of Spondias mombin L. (Family Anacardiaceae) crude methanol extract and fractions against Aedes aegypti (L.)

Ajaegbu, Eze Elijah; Younoussa, Lame ; Danga, Simon Pierre Yinyang; Uzochukwu, Ikemefuna Chijioke; Okoye, Festus Basden Chiedu

Abstract

The aim was to determine the repellent activities of creams formulated with different extract/fractions of Spondias mombin L. against female Aedes aegypti (L.). The repellent activity was carried out using blood-starved female mosquitoes inside net cages in the laboratory condition following World Health Organization protocol at three different concentrations, viz. 1, 2, and 4 mg/cm2 in the exposed area of human hands. Acetone together with white soft paraffin served as negative control and 12 % Odomos was used as the positive control. The cream formulations gave good protection against the mosquito bites and the repellent activity was dependent on the strength of the extract and fractions. Among the tested formulations, the maximum protection time was observed in MCE (180 min), HF (180 min) and DF (180 min) at 1 mg/cm2. From the results, it was clear that the MCE, HF and DF formulations can be used as natural mosquito repellents as alternatives to Odomos.

Keyword(s)

Aedes aegypti (L.), Dengue, Plant extract/fractions, Repellent, Spondias mombin L.

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