Pharmacognostic, phytochemical analysis and in-vitro antioxidant activity of Senecio edgeworthii Hook plant

Abstract

The objective of the present study was to investigate pharmacognostic, phytochemical and evaluate in vitro antioxidant properties of Senecio edgeworthii hook Plant. The study of leaf macroscopic features, microscopic features was undertaken and physicochemical parameters were evaluated using standard procedures as per WHO guidelines. In vitro antioxidant activity of S. edgeworthii plant was determined by application of standard methods. In microscopy of S. edgeworthii, leaf is having Upper epidermis, cuticle, multicellular covering trichomes. The transverse view of the lamina shows a single layer of closely packed palisade cells below the upper epidermis. In powder characteristics analysis, lignified xylem parenchyma, lignified fibres, stomata, epidermis, cork cell, xylem vessels, spiral vessels and trichomes were observed. A low amount of total ash acid insoluble ash and water-soluble ash indicate that the inorganic matter and non-physiological matter such as silica is less S. edgeworthii plant. The estimation of total phenolic content in the examined extracts showed SE-Chloro and SE-alcohol extract contains high phenolic content than SE-Oil and SE-Pet ether. The results of antioxidant evaluation based on the three models (DPPH, H₂O₂, and NO) used in this study revealed that chloroform and alcohol extract and flower oil of S. edgeworthii plant possess interesting antioxidant activity. The pharmacognostic, phytochemical analysis can contribute to the development of the quality control norms for this species. This plant may possess considerable antioxidant activities.