Synthesis of new imidazopyridine based 1,2,3-triazoles: Evaluation of antibacterial, antibiofilm and time kill studies

Abstract

The present communication elaborates the synthesis of 1,2,3-triazoles using click chemistry and their antibacterial studies. Structures of the synthesized compounds have been assessed by infra-red, NMR and mass spectroscopic methods. The title compounds have been screened for their antibacterial, antibiofilm and time kill studies. The molecules 5f, 5b, 5e, 5c and 3b have shown excellent activity and remaining compounds have also been found to exhibit moderate activity against the test organisms employed.