Montmorillonite K-10 supported palladium nanoparticles: A catalyst for the preparation of α-aminoynones employing copper free acyl Sonogashira reaction


 

V, Sureshbabu V; L, Roopesh Kumar; Alavandimat, Nanda H

Abstract

Palladium nanoparticles supported by Montmorillonite K-10 (MMT K-10) are utilized for the synthesis of α-amino ynones using amino acid chlorides and a mild base at room temperature. All the compounds were obtained in good yields. Furthermore, the catalyst is also utilized for the deprotection of protecting groups operating in peptide chemistry.


 


Keyword(s)

α-Amino ynones, Montmorillonite K-10 clay, nanoparticles, acyl Sonogashira reaction, hydrogenation

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