Development and standardisation of Laghu Sudarshan Churna – An Ayurvedic polyherbal formulation

Mangal, Anupam Kumar; Tomer, Rinku ; Jindal, Heena ; Prasad, Shyam Baboo; Singh, Harjeet ; Sharma, Bhagwan Sahai; Srikanth, Narayanam ; Dhiman, Kartar Singh

Abstract

Laghu Sudarshan Churna, LSC is an Ayurvedic polyherbal formulation employed for different types of jvaras (fevers). The present study was undertaken to prepare its standardised formulation and to standardise the finished product using quality control procedures mentioned in Ayurvedic Pharmacopoeia of India (API). For this, four batches of the finished products were prepared on a laboratory scale and performed the pharmacognostical parameters (macroscopic, microscopic and powder drug analysis); thin layer chromatography; quantitative physicochemical evaluation including loss on drying, total ash, acid-insoluble ash, alcohol & water soluble extractive values, and pH; & measuring the level of aflatoxins, microbial load, heavy metals and pesticide residues of the finished product. This study is the foremost effort to develop the standardised formulation along with the evaluation parameters for LSC. Thus, obtained results would be beneficial and will act as the reference for the standardisation of LSC.

Keyword(s)

Laghu Sudarshan Churna, Pharmacognosy, Standardisation, Thin layer chromatography

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